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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q96GN0
USC-OGP 2-DE database
:
Q96GN0
Q96GN0
General information about the entry
View entry in simple text format
Entry name
RGS10_HUMAN
Primary accession number
Q96GN0
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Regulator of G-protein signaling 10; Short=RGS10;.
Gene name
Name=RGS10
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0571
:
pI=6.01; Mw=19786
PLATELET_5-6
{PLATELET 5-6}
Homo sapiens (Human)
map experimental info
PLATELET_5-6
MAP LOCATIONS:
SPOT OGP-0844
:
pI=5.98; Mw=18206
PLATELET_6-11
{PLATELET 6-11}
Homo sapiens (Human)
map experimental info
PLATELET_6-11
MAP LOCATIONS:
SPOT OGP-1054
:
pI=6.01; Mw=19478
SPOT OGP-1056
:
pI=6.89; Mw=19029
Cross-references
UniProtKB/Swiss-Prot
O43665; RGS10_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
RGS10_HUMAN
Primary accession number
O43665
Secondary accession number(s)
A8K408 B1AMR8 Q6IAZ6 Q96GN0
Sequence was last modified on
August 14, 2001 (version 2)
Annotations were last modified on
March 15, 2017 (version 153)
Name and origin of the protein
Description
RecName: Full=Regulator of G-protein signaling 10; Short=RGS10;
Gene name
Name=RGS10
Encoded on
Name=RGS10
Keywords
3D-structure
;
Alternative splicing
;
Complete proteome
;
Cytoplasm
;
GTPase activation
;
Lipoprotein
;
Nucleus
;
Palmitate
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
;
Signal transduction inhibitor
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AF368902; AAK52979.1
; -; mRNA
EMBL
AF045229; AAC03783.1
; -; mRNA
EMBL
AF493934; AAM12648.1
; -; mRNA
EMBL
AK290773; BAF83462.1
; -; mRNA
EMBL
CR457008; CAG33289.1
; -; mRNA
EMBL
AL355273; CAI16486.1
; -; Genomic_DNA
EMBL
AC012468; CAI16486.1
; JOINED; Genomic_DNA
EMBL
AL355273; CAI16488.1
; -; Genomic_DNA
EMBL
CH471066; EAW49389.1
; -; Genomic_DNA
EMBL
CH471066; EAW49390.1
; -; Genomic_DNA
EMBL
BC009361; AAH09361.1
; -; mRNA
CCDS
CCDS31294.1; -. [O43665-3]
; .
CCDS
CCDS41572.1; -. [O43665-2]
; .
PIR
S71812; S71812
; .
RefSeq
NP_001005339.1; NM_001005339.1. [O43665-3]
; .
RefSeq
NP_002916.1; NM_002925.3. [O43665-2]
; .
UniGene
Hs.501200; -
; .
PDB
2DLR; NMR
; -; A=23-158
PDB
2I59; NMR
; -; A=22-157
PDB
2IHB; X-ray
; 2.71 A; B=9-152
PDBsum
2DLR; -
; .
PDBsum
2I59; -
; .
PDBsum
2IHB; -
; .
ProteinModelPortal
O43665; -
; .
SMR
O43665; -
; .
BioGrid
111933; 8
; .
DIP
DIP-50368N; -
; .
STRING
9606.ENSP00000358099; -
; .
iPTMnet
O43665; -
; .
PhosphoSitePlus
O43665; -
; .
SwissPalm
O43665; -
; .
OGP
O43665; -
; .
EPD
O43665; -
; .
MaxQB
O43665; -
; .
PaxDb
O43665; -
; .
PeptideAtlas
O43665; -
; .
PRIDE
O43665; -
; .
TopDownProteomics
O43665-3; -. [O43665-3]
; .
DNASU
6001; -
; .
Ensembl
ENST00000369101; ENSP00000358097
; ENSG00000148908. [O43665-1]; .
Ensembl
ENST00000369103; ENSP00000358099
; ENSG00000148908. [O43665-3]; .
Ensembl
ENST00000392865; ENSP00000376605
; ENSG00000148908. [O43665-2]; .
GeneID
6001; -
; .
KEGG
hsa:6001; -
; .
UCSC
uc001lee.4; human. [O43665-1]
; .
CTD
6001; -
; .
DisGeNET
6001; -
; .
GeneCards
RGS10; -
; .
HGNC
HGNC:9992; RGS10
; .
HPA
CAB004559; -
; .
HPA
HPA021305; -
; .
HPA
HPA058485; -
; .
MIM
602856; gene
; .
neXtProt
NX_O43665; -
; .
OpenTargets
ENSG00000148908; -
; .
PharmGKB
PA34362; -
; .
eggNOG
KOG3589; Eukaryota
; .
eggNOG
ENOG410YMJD; LUCA
; .
GeneTree
ENSGT00760000119142; -
; .
HOGENOM
HOG000233512; -
; .
HOVERGEN
HBG013233; -
; .
InParanoid
O43665; -
; .
KO
K16449; -
; .
OMA
PKSTAKW; -
; .
OrthoDB
EOG091G0BDG; -
; .
PhylomeDB
O43665; -
; .
TreeFam
TF315837; -
; .
Reactome
R-HSA-418594; G alpha (i) signalling events
; .
SignaLink
O43665; -
; .
SIGNOR
O43665; -
; .
ChiTaRS
RGS10; human
; .
EvolutionaryTrace
O43665; -
; .
GeneWiki
RGS10; -
; .
GenomeRNAi
6001; -
; .
PMAP-CutDB
O43665; -
; .
PRO
PR:O43665; -
; .
Proteomes
UP000005640; Chromosome 10
; .
Bgee
ENSG00000148908; -
; .
CleanEx
HS_RGS10; -
; .
Genevisible
O43665; HS
; .
GO
GO:0043679; C:axon terminus
; IEA:Ensembl; .
GO
GO:0005829; C:cytosol
; IDA:UniProtKB; .
GO
GO:0043197; C:dendritic spine
; IEA:Ensembl; .
GO
GO:0043025; C:neuronal cell body
; IEA:Ensembl; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:0005886; C:plasma membrane
; IBA:GO_Central; .
GO
GO:0001965; F:G-protein alpha-subunit binding
; IPI:UniProtKB; .
GO
GO:0005096; F:GTPase activator activity
; IDA:UniProtKB; .
GO
GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway
; IDA:UniProtKB; .
GO
GO:0009968; P:negative regulation of signal transduction
; IEA:UniProtKB-KW; .
GO
GO:0043547; P:positive regulation of GTPase activity
; IDA:UniProtKB; .
Gene3D
1.10.196.10; -
; 1; .
InterPro
IPR016137; RGS
; .
InterPro
IPR024066; RGS_subdom1
; .
Pfam
PF00615; RGS
; 1; .
PRINTS
PR01301; RGSPROTEIN
; .
SMART
SM00315; RGS
; 1; .
SUPFAM
SSF48097; SSF48097
; 1; .
PROSITE
PS50132; RGS
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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